Influenza Virus Vector Vaccine Market is Booming Worldwide – Analysts Expect Robust Growth During 2020 – QYResearch

This report focuses on demand and consumption of Influenza Virus Vector Vaccine in key countries, like U.S., Spain, Italy, France, UK, Germany, China and Japan, etc.

Key Findings 1: The Technology Principle of Influenza Virus Vector Vaccine

The vector technology of attenuated influenza virus has the same basic principle as that of adenovirus. It inserts the gene sequence of the target antigen into the genome of influenza virus, infects the human body with attenuated influenza virus, and expresses the relevant antigen through human cells. Attenuated influenza virus vector is a relatively new virus vector vaccine preparation technology which is not widely used in current vaccine development. It is considered an attractive vaccine carrier because of its ability to induce long-term mucosal, humoral and cellular immune responses.

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Figure 1.   Distribution of Gene-based Advanced Therapy Medicinal Products in Development Based on Viral or Plasmid Platform Used to Express Gene of Interest

Source: https://bioprocessintl.com/manufacturing/emerging-therapeutics-manufacturing/capacity-analysis-for-viral-vector-manufacturing-is-there-enough/

Key Findings 2: The Research and Development Progress of Influenza Virus Vector Vaccine

The university of Hong Kong attenuated influenza virus vector project is expected to conclude the pre-clinical study and apply for clinical trial by the end of April; The Russian company BiOCAD has also carried out the research on the new coronavirus vector vaccine, which is currently in the pre-clinical research stage.

Key Influenza Virus Vector Vaccine Developers and Suppliers Covered in This report

Table 1.   Global Representative Influenza Virus Vector Vaccine Developers/Suppliers and R&D Stage

Source: Above companies and QYResearch, 2020

• GREFFEX
• CanSino Biologics
• Academy of Military Medical Sciences
• XMU
• HKU
• Hualan Biological Engineering
• BravoBio
• Type Seven
• Type Eight

Key Findings 3: Evaluation of Influenza Virus Vector Technology Route

The current influenza virus culture technology is relatively mature. China issues about 30 million doses of influenza vaccine in batches every year, and the global annual production capacity of influenza vaccine is over 1.5 billion doses. The new influenza virus vector vaccine is expected to achieve mass production based on the existing influenza virus culture platform.

In the development of influenza virus vector vaccine to be administered by nasal spray, compared with the traditional injection delivery method is more convenient, which is conducive to the rapid expansion of the vaccination scope.

If successful, the novel coronavirus vector vaccine can prevent both novel coronavirus infection and influenza virus infection, with multiple advantages. Disadvantages: the exploration of adenovirus, vesicular stomatitis virus and other vectors has been relatively mature, compared with the research of influenza virus vectors is still in the early stage, its safety and immunogenicity are still uncertain.

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